Detalhe da pesquisa
1.
Effective treatment with the selective cytokine inhibitor BNZ-1 reveals the cytokine dependency of T-LGL leukemia.
Blood
; 142(15): 1271-1280, 2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37352612
2.
A fluorogenic substrate for the detection of lipid amidases in intact cells.
J Lipid Res
; 65(3): 100520, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38369184
3.
Genomic landscape of TCRαß and TCRγδ T-large granular lymphocyte leukemia.
Blood
; 139(20): 3058-3072, 2022 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35015834
4.
Frequent somatic TET2 mutations in chronic NK-LGL leukemia with distinct patterns of cytopenias.
Blood
; 138(8): 662-673, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33786584
5.
Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia.
FASEB J
; 36(10): e22514, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36106439
6.
Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia.
FASEB J
; 36(1): e22094, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34888943
7.
Sphingosine kinase-2 is overexpressed in large granular lymphocyte leukaemia and promotes survival through Mcl-1.
Br J Haematol
; 190(3): 405-417, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32124438
8.
Retroviral sero-reactivity in LGL leukaemia patients and family members.
Br J Haematol
; 188(4): 522-527, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31608437
9.
TRAIL mediates and sustains constitutive NF-κB activation in LGL leukemia.
Blood
; 131(25): 2803-2815, 2018 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29699990
10.
The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia.
Haematologica
; 105(3): 687-696, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31123028
11.
Pivotal role of mitophagy in response of acute myelogenous leukemia to a ceramide-tamoxifen-containing drug regimen.
Exp Cell Res
; 381(2): 256-264, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31112736
12.
Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation.
J Lipid Res
; 60(6): 1078-1086, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962310
13.
Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.
J Lipid Res
; 60(9): 1590-1602, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31363040
14.
Vitamin D pathway activation selectively deactivates signal transducer and activator of transcription (STAT) proteins and inflammatory cytokine production in natural killer leukemic large granular lymphocytes.
Cytokine
; 111: 551-562, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455079
15.
Vitamin D in hematological disorders and malignancies.
Eur J Haematol
; 98(3): 187-197, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27743385
16.
Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia.
J Lipid Res
; 57(7): 1231-42, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27140664
17.
Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias.
Carcinogenesis
; 37(8): 810-816, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27207659
18.
Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
Biochim Biophys Acta
; 1851(7): 919-28, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25769964
19.
Suberoylanilide hydroxamic acid (SAHA) and cladribine synergistically induce apoptosis in NK-LGL leukaemia.
Br J Haematol
; 168(3): 371-83, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25284154
20.
Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells.
Biochim Biophys Acta
; 1831(12): 1657-64, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23939396